What Are the Potential Health Benefits of the Keto Diet?

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What Are the Potential Health Benefits of the Keto Diet?

Introduction

In the realms of dietary cultures, no other regimens have the level of attention of the general public as well as created the level of excitement besides the ketogenic diet. Evolving from a therapeutic approach used in the 1920s for treating people with epilepsy, this low carb, high fat diet has moved away from its roots in medicine to become a foundation of present-day wellness practice. Nowadays, it’s magnetic power is not limited to weight loss, rather expands to realms of cognitive enhancement, disease management and even longevity. While traversing the maze of health and nutrition, uncovering the compelling threads of the seldom explored aspects of the keto diet broadens a picture woven with both potential and precaution. Only the outer layer of this issue is the consideration of weight loss, and beyond that is a set of metabolic intricacies, which at times turns into strength, and at others, stumbles into certain health repercussions.

What Are the Potential Health Benefits of the Keto Diet?

1. Keto Diet Overview

The keto diet is a high-fat, low-carb diet that aims to push the body to ketosis, with the body using its stored fat as the main source of fuel, which leads to weight loss and other health benefits. Notwithstanding that, the keto diet may not be suitable for everyone; therefore, seeking advice from a healthcare professional is a must before adopting a new diet (1, 2).

Although the keto diet was only a fashionable trend a few years ago, it has gained popularity, becoming an approved regimen when followed correctly and even comparing its benefits with the life-sustaining Mediterranean diet (3).

Mainstreaming low-carbohydrate diets is where the future is headed, with highlighted trends including personalised low-carb plans targeting one’s specific needs, the growing emphasis on the use of plants, and the skyrocketing of Mediterranean-style low-carb diets (2).

As fast as the keto diet has gained the spotlight, experts have come up with a new way of dieting to be embraced in 2024 that is personalised macros, with an emphasis on whole foods, supplementation, and meal creation for it to be exciting and delicious (4).


2. Historical background and development of the keto diet

The historical setting of the ketogenic diet (KD) and its development is deeply rooted in its adoption as a treatment for epilepsy in the 1920s. Modern physicians employed a device called the KD to imitate the physiological process of fasting that has been utilised since at least 500 B.C (5) to treat epilepsy. The ketogenic diet (KD) was used for more than two decades; during this period antiepileptic drugs entered into clinical practice (5).


The classic ketogenic diet, which contains a “4:1: 1 ratio of fat to protein and carbohydrates using the 1920s method of Gustav Petermann paediatrician (6). In the 1960's, researchers found that medium-chain triglycerides (MCTs) produce more ketone bodies per unit of energy than long-chain triglycerides (LCTs), and MCTs are the building blocks of an MCT-based ketogenic diet (6).


The popularity of KD, a ketogenic diet, skyrocketed in the 90’s after a TV program emphasised its efficiency in treating epilepsy (7). Nowaday the ketogenic diet (KD) is not only being used to treat epilepsy but also to lose weight and for other health benefits (7). Design of the ketogenic diet (KD) variants, for example, the modified Atkins diet, has been proposed as a cost-effective (KD) alternative in developing countries (6).


The ketogenic diet (KD) has a long history of use, with its origins in ancient Greek medicine and its modern development as a treatment for epilepsy in the 1920s (7).The ketogenic diet (KD) has evolved over time, with changes in its protocols and applications, but its basic principles have remained the same: a diet containing a significantly low amount of carbohydrates but a high level of fat that results in a metabolic condition of ketosis (6).


3. An overview of the benefits of losing weight and burning fat

Weight loss can produce several health benefits, and feeling better is one of the most profound aspects of losing weight. One of the crucial advantages is lowering cardiovascular risk indicators like high blood pressure and cholesterol levels (8). In 2023, the first GLP-1 medications, like Zepbound, were approved, which may help people lose weight and lower their cardiovascular risks (8).

The fat-burning effect of exercise can also be advantageous, with the power to boost insulin sensitivity and limit type 2 diabetes risk (9). Apart from that, the loss of fat triggers weight loss, which is beneficial for joint health, decreases the risk of certain kinds of cancer, and provides improved sleep (10).

While considering weight loss and fat burning, one should keep in mind that such diets are not appropriate for everyone. Prior consultation with a healthcare professional is highly recommended (10).


4. Potential health benefits of the keto diet

4.1. Neurological, cognitive, and psychological benefits

1. The effect of ketosis on brain function

Ketosis, a phenomenon caused by a ketogenic diet, is a metabolic state and is known to affect brain function in several different ways. The brain's energy metabolism is modified by ketone bodies (KBs), which can safeguard neurons from a glucose deficit and may be involved in neurodegenerative diseases that affect brain metabolism. A ketogenic diet is characterized by higher amounts of KB passing through the metabolic processes, causing ketosis that affects mitochondrial metabolism, cell signalling, and neurotransmitter function. Furthermore, KBs can lower oxidative stress, inflammation, and toxicity; these elements may promote cognitive function and might be useful in some neurologic issues, as per research (11).


The brain’s utilisation of ketones appears to be largely dependent upon the ketones’ concentration in the blood. This condition can cause other side effects, such as a lack of enough ketone bodies that may act as an alternative energy source for the brain. They have been found to control brain energy metabolism, thus functioning as a source of energy that promotes the treatment of neurodegenerative diseases. Research has shown that ketosis may be able to modify cognitive function and can possibly be used to treat cases like Alzheimer's disease and Parkinson's disease (12, 13).


Ketosis through ketogenic dieting acts in different ways to affect brain functions such as energy metabolism, supporting the brain, providing neuroprotective effects, and offering possible therapeutic benefits in neurological disorders. But, it should be remembered that the use of a ketogenic diet and keto therapeutic methods should be individualised and supervised by professionals to guarantee their safety and effectiveness (11).


2. Improving cognitive performance

Studies have demonstrated that a ketogenic diet is linked with enhancement of cognitive function. The case report published in 2023 showed a 47-year-old woman with both Down syndrome and Alzheimer's disease who experienced a considerable improvement of her cognition through following a therapeutic ketogenic diet (14). 

A paper review from the most basic research to clinical practice also targeted the neuroprotective and cognitive benefits of the ketogenic diet for neurodegenerative and psychiatric disorders (15). As a result, an article in ‘Tomorrow Bio’ suggested the benefit of a ketogenic diet to support mental clarity, focus, memory and cognitive performance by providing constant energy (16).


The ketogenic diet has been found to be beneficial for those with Alzheimer's disease, epilepsy and Parkinson's disease, and in some cases leads to improved cognitive abilities and memory recovery.Ketogenic diet has been shown to lead to major cognitive enhancements in subjects with neurodegenerative disorders and other cognitive problems (17).


Ketone bodies' neuroprotection and stable energy source which are induced by a ketogenic diet are thought to be the main reasons for its cognitive improvement ability. Nevertheless, it should be mentioned that the ketogenic diet may not be a suitable one for everyone, and thus seeking advice from a healthcare practitioner is in order prior to a switch to this diet (14), (16).


3. Potential therapeutic role in neurological disorders
To date, the ketogenic diet (KD) has proven to be a viable treatment option for neurodegenerative disease to improve gut microflora and neurological symptoms.
  There is clear evidence in a systematic review that KD can affect the gut microbiota, which in turn positively influences the development of neurological disorders and attention/memory function in a systematic review (18).
Another review emphasized the neuroprotective effects of the KD ketogenic diet in people with Alzheimer's and Parkinson's disease. Prevention can also reduce the burden of other neurological diseases (19).
Neuropsychiatric diseases were addressed in the scoping review, which found an association between each disease and micromorbidities. Therefore, it is suggested that KD could also be effective in preventing neurological diseases, including Alzheimer's and Parkinson's disease (15).
One brief study stated that when our body switches to a ketogenic diet, we experience a change in our immunity and show a response associated with adaptive immunity (20). A large-scale examination provides insight into the therapeutic value of the ketogenic diet in neurological disorders, identifies its potential mechanisms of action, and points out the difficulties of nutritional management as a therapeutic option (21).
These studies published in 2023 and 2024 are the latest results of studies and monotherapy as treatments for neurological disorders.


4.2. Cardiovascular health benefits

1. The effects on blood lipid levels.
The lipid profile of the blood under the keto diet’s effect may be different among people. Not all the studies have revealed a decrease in triglycerides and an increase in high-density lipoprotein-cholesterol (HDL-C) levels, while others have reported elevations in low-density lipoprotein-cholesterol (LDL-C) levels, with the strongest effect observed among the normal-weight group (22, 23).
Results of a 2023 case report revealed a pronounced LDL-C rise in a normal-weight male associated with a ketogenic diet, requiring close blood lipid assessment in those on a ketogenic diet (22).
From the 2023 studies’ review, one might find the following: staying on the keto diet for more than two years is associated with such health conditions as cognitive decline, nutritional deficiencies, kidney stones, heart disease, and muscle loss (24).
The keto diet can raise LDL-C levels above the recommended range in some cases, especially among normal-weight adults. Along with the keto diet, one should keep a careful eye on the blood lipid profiles of all the members. However, it is vital to mention that the keto diet may not be suitable for each person, and thus, individuals should seek advice from their healthcare provider before starting a diet or exercising program (22, 23).


2. Effects of risk factors for cardiovascular disease
The latest research points to the ketogenic diet (KD) with possible benefits in heart disease prevention (CVD) (25, 26).
. A detailed review of literature on this topic has shown that KD affects CVD prevention and treatment mechanisms in a multifactorial way: improvement of blood lipid profile, anti-inflammatory and cardioprotective effects, and blood pressure control and other CVD risk factors through weight loss (25).
A systematic review published in the American Journal of Clinical Nutrition in 2019 found that KD can significantly lower LDL cholesterol levels, a serious risk factor for heart disease (26).
I think that undoubtedly, However, a study reported at the American College of Cardiology’s Annual Scientific Session together with the World Congress of Cardiology in 2023 indicates that a diet low in carbohydrates and high in fat, like the KD, was positively correlated to cardiac events (27). The study was observational; it cannot prove the causal relationship.
The recent reports on the beneficial role of the KD in lowering CVD risk still need further studies to fully comprehend the impacts of the KD on cardiovascular health.

4.3. Metabolic and endocrine health benefits

1. Role in the management of type 2 diabetes

The ketogenic diet has already proven its positive effect on controlling type 2 diabetes. A systematic review that was published in 2022 indicates that, on average, the diet lowered measurements of blood glucose by 1.29 mmol/L, reduced blood fractions including LDL, triglycerides, and increased blood cholesterol concentration in patients with type 2 diabetes (28).

In another meta-analysis in 2022, the comparison of health outcomes of the ketogenic diet and that of the standard diet recommended for type 2 diabetes showed that the ketogenic diet favourably affected the glycemic control and lipid profiles in type 2 diabetes and significantly contributed to weight loss (28).

Nevertheless, better-designed studies must be conducted to get an exhaustive understanding of the risks and benefits of the keto diet for managing type 2 diabetes. It should be noted, however, that prior to starting any diet or exercise plan, people are advised to consult healthcare professionals (28).


2. The Keto Diet's Impact on Insulin Sensitivity and Blood Sugar Control
A ketogenic diet is shown to have an important role in improving insulin sensitivity and blood glucose levels. As manifested in experiments, low-carbohydrate diets, like the ketogenic diet, can improve insulin sensitivity even without weight loss (29).
The metabolic state connected to nutrition, ketosis, has favourable effects on glucose management by lowering glucose intake and promoting insulin sensitivity (26).
The ketogenic diet is associated with decreased need for the drug insulin administered to type I diabetes patients taking insulin (28).
A systematic literature search of randomised controlled trials conducted found that the ketogenic diet is particularly helpful in weight management and lipid profile control in overweight individuals, particularly among those with pre-existing diabetes. While low-fat diets proved to be effective in achieving overall metabolic control, the ketogenic diet exhibited more impressive results in the areas of glycemia, weight reduction, and insulin sensitivity (26).
Research reveals that the keto diet can improve insulin sensitivity and decrease blood sugar levels; these two actions are important in diabetes management and obesity (30).
During this period, debates over the long-term use, safety, and effectiveness of a very low-carbohydrate, ketogenic diet in comparison with the present dietary health guidelines are still ongoing (31).


3. Potential benefits for polycystic ovary syndrome (PCOS)

A ketogenic diet shows potential benefits for women with polycystic ovary syndrome (PCOS) by improving insulin sensitivity and hormone balance. A 12-week study of 14 women with PCOS showed significant improvement in blood sugar and insulin levels, and the better scores for insulin resistance, the greater insulin sensitivity (32).

In a pilot study involving 11 women with PCOS following a low-carbohydrate, ketogenic (LCKD) diet for 24 weeks, body weight, percent free testosterone, LH/FSH ratio, and a significant decrease in fasting blood insulin (33).

However, it should be noted that the long-term effects of the ketogenic diet on PCOS are not yet fully understood, and more research is needed to determine the safety and efficacy of this regimen for managing PCOS (34). In addition, the ketogenic diet can have complications, such as an. increase in cholesterol levels and difficulty maintaining long-term compliance (32, 34).


4. Raise HDL ("good") cholesterol.

There are still no clear results concerning HDL cholesterol levels as a result of the ketogenic diet, and hence, further research is required. Certain studies show that the keto diet can raise your HDL cholesterol levels, whereas others reveal it can lower them. In a meta-analysis of trials that looked at normal-weight adults, the keto diet was found to have an effect contrary to the general trend of cholesterol and LDL cholesterol levels, but an increase in HDL cholesterol levels would compensate for this (35).

According to other studies, a one-year keto diet may cause LDL cholesterol levels to soar (25). A randomised controlled trial of women with hyperinsulinemia and excessive body weight found that the HDL concentration increased significantly in those women who were following a low-calorie ketogenic diet (25).

It is imperative to note that the ultimate effects of the keto diet on cholesterol levels are not yet completely known, and more research is required in order to assess the safety and efficacy of this dietary method for the purpose of lowering one’s cholesterol levels. Furthermore, the keto diet is known to be challenging since it is associated with increased levels of cholesterol and compliance with it for the long term (25, 36).


4.4. The benefits of mental health and increased energy

1. Relieving many symptoms of anxiety and depression.

The ketogenic diet (KD) has been linked to plausible advantages in the treatment of mood and anxiety disorders. In many studies emerging, some evidence also suggests that the KD can benefit mood, anxiety, and depression symptoms. Thus, an article published in the same systematic review in BJPsych Open describes the probable usefulness of the KD to relieve symptoms of anxiety, depression, and psychosis in psychiatric populations (37).

In the 2024 NPR article, it was shown that the KD study is ongoing and being tested to find out the effect on mental disorders like bipolar disorder, schizophrenia, and depression. Some patients reported very good results and said that their symptoms were improving (38).

Moreover, a study published in 2023 on Medical News Today revealed that the KD might also alleviate depression through many mechanisms, including improving mitochondrial function, decreasing oxidative stress, regulating insulin function, increasing GABA, and reducing inflammation (39).

Nevertheless, it should be borne in mind that KD is not appropriate for everyone, and we recommend seeking medical advice with a healthcare professional before going about a new diet or exercise plan (37, 40).


2. Raise the energy levels and stamina.

As far as energy levels and endurance are concerned, the ketone diet (KD) has been demonstrated to maintain rather constant energy sources using ketone bodies as an alternative fuel (41). Such results can result in increased endurance and physical performance, especially in endurance athletes. Furthermore, the KD may decrease oxidative stress and inflammation, which can cause tiredness and energy reduction (42).

Nevertheless, it is important to highlight that the KD may not be suitable for everyone, and it is advisable to consult with a healthcare professional before starting any new diet or exercise routine. Also, the transition period to KD may need an adjustment period where individuals may experience fatigue and low energy levels before experiencing the potential benefits of KD (42).


3. Improve sleep quality.

The ketogenic diet (KD) has been linked with the possibility of improving sleep quality. Although the evidence is yet to be sufficient, it has been shown that the KD may improve sleep duration and quality. For instance, in 2023, a study was published in the Journal of Clinical Sleep Medicine that found that a KD improved sleep quality and lessened daytime sleepiness in individuals with obstructive sleep apnea (43). Furthermore, a 2024 study in the Journal of Sleep Research concluded that a KD improved sleep quality and reduced insomnia symptoms in people with type 2 diabetes (44).

The probable sleep benefits of the KD may be due to the impact of the diet on brain function and neurotransmitter activity. It has been demonstrated that KD promotes mitochondrial function, reduces inflammation, and improves brain energy metabolism, which may lead to sleep benefits (45). Moreover, the KD may raise the synthesis of gamma-aminobutyric acid (GABA), a neurotransmitter that has relaxing functions in the brain and can help calm down (45).

However, it should be remembered that the evidence on the effects of the KD on sleep is still quite limited, and more studies should be done to fully understand its possible benefits and risks. Besides, the KD may not be right for everybody, so talking with a healthcare professional prior to starting any new diet or workout is advised (43, 44, 45).


4. Improves cognitive function and memory.

The ketogenic diet has been shown to have cognitive-enhancing effects in the domains of working memory, reference memory, and attention (17). Studies have shown that the ketogenic diet may be beneficial to those with non-epileptic conditions as well as to healthy individuals (17).

A study with people who have early signs of dementia showed that a high-fat, low-carbohydrate diet may improve brain function and memory (46). Another study showed that the medium-chain triglyceride-based ketogenic formula could be useful in patients with mild-to-moderate cognitive impairment (47). The ketogenic diet has also been found to improve memory in cases of mild cognitive impairment (48, 49).

Conclusive results were restricted by studies with small sample sizes, the absence of control groups and randomization, and the lack of objective measures of cognition (17). Further research is necessary on the therapeutic application of ketogenic diets for cognitive function and in patients with dementia or mood disorders (17).


4.5. Other health benefits that were not expected

1. Improving healthy liver function.

Liver health could be an advantage of the ketogenic diet. It has been shown that diet can be used as a tool for the prevention and reversal of nonalcoholic fatty liver disease (NAFLD) (50, 51). The diet is capable of doing that through the reduction of inflammation and the improvement of the metabolic complications involved in NAFLD (51). Moreover, the ketogenic diet has also been demonstrated to have the effects of improving insulin sensitivity and glycemic control, which can help cut down on the risk of developing and worsening NAFLD (50).

The diet can also cause cholesterol levels to increase in the blood and induce increases in liver enzymes, which may be a risk factor for NAFLD (52). Ketogenic diet patients should therefore be monitored with laboratory blood tests of ketones, lipids, and liver enzymes, as well as frequent assessments of cognitive function and energy levels (52).


2. Decreased appetite and fewer cravings

Ketogenic diet has been proven to minimise cravings and control appetite by using different mechanisms. Studies have shown ketogenic diets to suppress appetite, resulting in less hunger and less desire to eat, which may be a factor contributing to improved adherence to weight loss regimens (53). The fat composition of the diet, the reduction in food cravings as well as the lowering of appetite-stimulating hormones such as insulin and ghrelin lead to its appetite suppressant effect (54).

Furthermore, ketosis increases satiety and reduces appetite, further supporting weight loss through caloric intake reduction (26). The potential of the ketogenic diet for rapid weight loss without the increase in hunger at the same time makes it a good candidate for weight loss (53).

The role of the ketogenic diet in appetite control is of clinical importance, as appetite is an important determinant of body weight regulation. It has been discovered through studies that people who are on ketogenic diets have experienced being less hungry in the fasted state and fuller after a meal. With diet-induced weight loss taking place, hunger feelings (and increased ghrelin secretion) are suppressed under ketosis (53).

Apart from the encouraging perspective that the ketogenic diet can help in adherence to weight loss interventions, more studies are needed to establish the relationship between the ketogenic diet and control of appetite (53).


3. Potential therapeutic role in cancer
There have been suggestions that the ketogenic diet can be used as a supportive therapy in patients with cancer, but its long-term consequences on survival rates are still controversial. Interestingly, the study of 55 advanced-stage cancer patients who followed the ketogenic diet for more than 3 months reported a median overall survival of 32.2 months and a three-year survival rate of 44.5% (55). But there were some limitations to the study; for example, a small sample size and another limitation of a control group were missed (55).
The ketogenic diet, with its well-defined features, has been demonstrated to be safe and effective in the management of fasting glucose, improving insulin sensitivity, and changing body composition in women with stage IV metastatic breast cancer (56). The results of the Keto-CARE trial showed that a WFKD maintained through balanced nutritional counselling brought about weight loss, cardiovascular protection, and improved fasting plasma glucose (56).
Notwithstanding, the ketogenic diet may also evoke undesired side-effects in mice that have pancreatic and colorectal cancer, accelerating cachexia (57). Researchers noticed that a ketogenic diet and corticosteroids co-synthesizing may prevent cachexia in tumour-carrying mice, with their tumours lessened and their life span prolonged (57).
The ketogenic diet demonstrated cancer patients' benefits, but more research is required to reveal optimal approaches and possible long-term effects and side effects (55, 56, 57).


4.Reducing signs of inflammation

The ketogenic diet has proven to be helpful in lowering the markers of inflammation through various mechanisms. A study was published in the journal Communications Biology in 2023, and it showed that the ketogenic diet can also be used to temper SARS-CoV-2-triggered systemic reprogramming and inflammation. The study found a significant decrease in metalloproteases and a great increase in inflammatory homeostatic protein transcription in the heart, with a decline in serum pro-inflammatory cytokines under the ketogenic diet (58).

Furthermore, an article of review published in Immuno in 2022 suggested that KD lowers inflammation, and the inhibition of the NLRP3 inflammasome by β-hydroxybutyrate (BHB) is one of the anti-inflammatory effects (59). These results highlight the possibility of the anti-inflammatory benefits of the ketogenic diet.

The applied review article additionally discussed the immune modulatory effects of the ketogenic diet in different disease conditions and the anti-inflammatory effects of the ketogenic diet as well. The study gave an image of the possibility of the ketogenic diet regulating the immune system in different disease states; therefore, this mechanism showed the anti-inflammatory properties of this diet (59).

Adapting the ketogenic diet can help reduce inflammatory markers, based on several studies and reviews, which may further lead to its ability to minimise inflammatory processes. Nevertheless, further studies are required to thoroughly understand the effects of these observations on the use of this diet for the management of inflammatory diseases.


5. Improve skin health

The use of a ketogenic diet may provide some beneficial effects to improve the health of the skin. Emerging data points out that the anti-inflammatory effect of the diet is very beneficial in the treatment as well as the prevention of different skin diseases like acne, psoriasis, and hidradenitis suppurativa. (60) Moreover, the diet’s ability to lower inflammation and oxidative stress may be a contributing factor in healthier skin, thus preventing skin cancer and reducing the usefulness of varicose veins (61).

There are links between a ketogenic diet and the overall health of the skin, as well as a reduction in the condition of acne (2, 6). Furthermore, individual reactions to the ketogenic diet can differ (61), and it is therefore recommended to consult a healthcare professional before making any dietary adjustments.


5. What are the possible side effects of the keto diet? 

Keto flu: Typical symptoms include headaches, fatigue, muscle pains, nausea, and diarrhoea, while the body is using fat for energy (62).

Dehydration: More frequent urination produces water loss, which in turn results in dehydration and many electrolyte imbalances (62). 

Gastrointestinal issues: constipation occurs because there is less fibre intake (62). 

Cardiovascular risk factors: the high levels of "bad" cholesterol that are often associated with heart attacks, strokes, and peripheral artery disease (2, 63).

Increased risk of type 2 diabetes complications: The high-protein ketogenic diets may only worsen the already-present kidney dysfunction (2). 

Nutrient deficiencies: Restrictive diets could cause some deficiency of vitamins, minerals, and needed nutrients (2). 

Disordered eating patterns: craving salt and sugar because of changes in the regulation of appetite (62). 

Long-term safety, efficacy, and sustainable lifestyle are in question, while the diet might not be maintained easily (2, 63).


6. What are the means to mitigate the negative side effects of the keto diet?

To alleviate the side effects of the keto diet, particularly the keto flu, consider the following strategies based on recent research:To alleviate the side effects of the keto diet, particularly the keto flu, consider the following strategies based on recent research:

Stay hydrated sufficiently by taking water and pushing for water-filled meals like watermelon and lettuce (64).

Obtain sufficient amounts of electrolytes by adding salt to your food or using electrolyte replacement drinks (65, 64).

An intergradual approach to the introduction of the keto diet is recommended (for example, start with partial cutbacks but do not make too many carbohydrate restrictions at one time) (65).

Consume the calories as recommended daily; give healthy fats priority while avoiding unnecessary nausea (65).

Take it easy during the first days of your health status change; refrain from exhausting yourself (65).

Relieve constipation through diets that are rich in fiber, such as non-starchy vegetables, nuts, and seeds (66).

Monitor your body's nutrition and check the possible vitamins and minerals that can be deficient in a high-fat diet (67).

It is worth mentioning that while responses to the keto diet vary from one person to another, help should be sought from qualified professionals in case of need.

Conclusion

However, the travel of the ketogenic diet landscape offers a scenery with multiplexed features and an ambience of both promise and caution. From its humble prefix as an instrument for epilepsy therapy to its current renaissance as a solution for the whole range of health issues, the Keto diet is an amazing trend that can hardly be ignored by the health enthusiasts worldwide. However, as we weigh the advantages with the hopes of the benefits of diets, we should do so gently, bearing in mind individual complexities and challenges of the diets in the biological systems. In the quest for the continually changing story of health and wellness, let us go with a mix of curiosity and awareness, led by a paradigm of practising based on evidence and holistic wellbeing.

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